Sabtu, 08 Februari 2014

Focusing On Important Aspects Of Glioblastoma

By Rob Sutter


GEN published an article that talked about a serious condition by the name of glioblastoma. Many people may be familiar with the term but those who are not should know that this is the most prevalent and aggressive type of brain cancer seen. It is also the one that accounts for about 15% of tumors seen in adults. It's apparent that, with so many different studies being done with this condition serving as the focus, certain aspects will be focused on more than others in the long term.

What is it that makes glioblastoma tumors as severe as they are, you may wonder? The report went into detail about the litany of different cell types which exist in tumors, stem cells arguably having the greatest impact of them all. These are the ones which serve in the way of cell perpetuation and growth in the long term, which is something that brings such a level of seriousness to the condition mentioned before. It is also one of the reasons for the presence of such organizations on the matter, Voices against Brain Cancer being one such name.

There was a study done by a group of researchers seen within the Montreal Neurological Institute and Hospital at McGill University. The group in question put to use an in vivo mouse model that would oversee the activity seen in human GBM-derived brain tumor initiating cells. FOXG1 and TLE were the two proteins looked into and it was determined that they could play into the shifts seen in various genes as well. It's clear that there is attention brought to the potential regulators of this serious condition.

I believe that it is important to look at certain methods in the name of research, seeing as how these cells can work to tremendous degrees. In addition, they may not be fully eradicated if typical surgery followed by chemo or radiation therapy is followed through with, meaning that the need to find more effective methods is strong. The researchers mentioned before made the claim that FOXG1 and TLE can come together. This would be done for the sake of causing tumor activity to decrease, if not stop completely.

Glioblastoma is oftentimes regarded as one of the more serious conditions in the body but the potential for improvement over the course of time is apparent. There are various stories to consider and each of them can possibly be found on the Internet with enough effort. If you were to look at one story from another, you may see that certain components will be given more attention than others. The potential that they can hold is a point that, in my mind, makes research that much more worthwhile.




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